Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14021454 | 0.86 | KDM4E (0.39) | KDM4EALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL4820235 | 0.85 | PGR (0.39) | KDM4EALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL4915592 | 0.83 | ALDH1A1 (0.37) | KDM4EALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL4751035 | 0.82 | ALDH1A1 (0.39) | KDM4EALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL14022484 | 0.80 | KDM4E (0.33) | KDM4EALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL13889225 | 0.77 | ALDH1A1 (0.39) | KDM4EALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL4751693 | 0.77 | DHODH (0.39) | KDM4EALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL4752262 | 0.75 | ALDH1A1 (0.36) | KDM4EALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL4748841 | 0.75 | ALDH1A1 (0.39) | KDM4EALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL4813032 | 0.74 | MAP2K1 (0.35) | KDM4EALDH1A1MAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008135824-A1 | OXYALKYLPYRAZOLE COMPOUNDS USEFUL IN THERAPY | PFIZER LIMITED (GB) | 2008-11-13 | — | — | WO | disclosed |