Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.33 |
| ▸ | PGR | P06401 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4813064 | 0.91 | KDM4E (0.37) | MAP2K1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL14021454 | 0.88 | KDM4E (0.39) | L3MBTL1KDM4EALDH1A1HTTMEN1 | |
| SCHEMBL4915592 | 0.85 | ALDH1A1 (0.37) | L3MBTL1KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL4820235 | 0.76 | PGR (0.39) | L3MBTL1KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL4962255 | 0.76 | MRGPRX4 (0.40) | FFAR4PGRAR | |
| SCHEMBL4959655 | 0.75 | MRGPRX4 (0.39) | FFAR4PGRAR | |
| SCHEMBL4751032 | 0.74 | KDM4E (0.39) | L3MBTL1KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL4748844 | 0.74 | PGR (0.38) | MAP2K1KDM4EMAPTPGRHSD17B10 | |
| SCHEMBL4976120 | 0.74 | PGR (0.46) | FFAR4PGRAR | |
| SCHEMBL4114375 | 0.73 | MRGPRX4 (0.36) | FFAR4PGRAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008135824-A1 | OXYALKYLPYRAZOLE COMPOUNDS USEFUL IN THERAPY | PFIZER LIMITED (GB) | 2008-11-13 | — | — | WO | disclosed |