Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 6/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | F2 | P00734 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | XBP1 | P17861 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | VDR | P11473 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31668593 | 0.80 | GAA (0.40) | KDM4EMAPTKMT2AALDH1A1HPGD | |
| SCHEMBL12904736 | 0.80 | GAA (0.40) | KDM4EMAPTKMT2AALDH1A1HPGD | |
| SCHEMBL2557909 | 0.77 | EPHX2 (0.56) | EPHX2KDM4EKMT2AALDH1A1HPGD | |
| SCHEMBL4751176 | 0.68 | GPR84 (0.37) | EPHX2GPR84KDM4EMAPTKMT2A | |
| SCHEMBL31588015 | 0.66 | GAA (0.42) | KDM4EMAPTKMT2AALDH1A1HPGD | |
| SCHEMBL10441919 | 0.66 | GAA (0.42) | KDM4EMAPTKMT2AALDH1A1HPGD | |
| SCHEMBL3162219 | 0.65 | GRIN1 (0.42) | EPHX2MAPTKMT2AMEN1NPSR1 | |
| SCHEMBL10441587 | 0.65 | LMNA (0.42) | KDM4EMAPTKMT2AALDH1A1HPGD | |
| SCHEMBL10441985 | 0.65 | LMNA (0.42) | KDM4EMAPTKMT2AALDH1A1HPGD | |
| SCHEMBL8124150 | 0.65 | HDAC6 (0.42) | EPHX2KMT2AMEN1GRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008135041-A1 | ADAMANTYLOXYAMINE DERIVATIVES AND RELATED COMPOUNDS FOR USE AS NMDA AND/OR DPP-4 MODULATORS FOR THE THERAPY OF CNS DISEASES AND DIABETES | SCHEBO BIOTECH AG (DE) | 2008-11-13 | — | — | WO | disclosed |