Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNK | O75909 | 2/20 | 0.39 |
| ▸ | CDK9 | P50750 | 2/20 | 0.39 |
| ▸ | CCNT1 | O60563 | 8/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.34 |
| ▸ | PTGES | O14684 | 2/20 | 0.34 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.33 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.33 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.33 |
| ▸ | PAK4 | O96013 | 1/20 | 0.33 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4751196 | 0.84 | VCP (0.44) | HDAC7HDAC11HDAC8HDAC6PTGES | |
| SCHEMBL4751199 | 0.84 | VCP (0.44) | HDAC7HDAC11HDAC8HDAC6PTGES | |
| SCHEMBL2137199 | 0.71 | HDAC7 (0.45) | HDAC7HDAC11HDAC8HDAC6 | |
| SCHEMBL3957046 | 0.69 | NPC1 (0.51) | — | |
| SCHEMBL13438929 | 0.68 | PRMT5 (0.39) | CCNKCDK9CCNT1 | |
| SCHEMBL11935245 | 0.68 | PRMT5 (0.39) | CCNKCDK9CCNT1 | |
| SCHEMBL13563354 | 0.67 | NPC1 (0.45) | — | |
| SCHEMBL17733741 | 0.65 | HRH4 (0.49) | CCNKCDK9CCNT1PAK4PAK1 | |
| SCHEMBL9885082 | 0.65 | HRH4 (0.49) | CCNKCDK9CCNT1PAK4PAK1 | |
| SCHEMBL11936324 | 0.65 | FBP1 (0.46) | PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008134228-A1 | BENZOXAZOLE COMPOUNDS | H. LUNDBECK A/S (DK) | 2008-11-06 | — | — | WO | disclosed |