Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.30 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4104626 | 0.89 | PGR (0.42) | PGRMEN1KMT2AALDH1A1GLA | |
| SCHEMBL4107682 | 0.89 | PGR (0.46) | PGRMEN1KMT2AALDH1A1GLA | |
| SCHEMBL4110642 | 0.88 | PGR (0.41) | PGRMEN1KMT2AALDH1A1GLA | |
| SCHEMBL4748729 | 0.85 | KDM4E (0.32) | MEN1KMT2AALDH1A1KDM4ELMNA | |
| SCHEMBL4748737 | 0.83 | PGR (0.44) | PGRMEN1KMT2AALDH1A1GLA | |
| SCHEMBL4748819 | 0.83 | PGR (0.37) | PGRMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL4752257 | 0.82 | PDE10A (0.34) | MEN1KMT2AALDH1A1KDM4ELMNA | |
| SCHEMBL4104566 | 0.82 | PGR (0.46) | PGRMEN1KMT2AALDH1A1GLA | |
| SCHEMBL4752250 | 0.82 | BRD2 (0.33) | PGRALDH1A1KDM4ELMNA | |
| SCHEMBL4111142 | 0.80 | PGR (0.45) | PGRMEN1KMT2AALDH1A1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008135824-A1 | OXYALKYLPYRAZOLE COMPOUNDS USEFUL IN THERAPY | PFIZER LIMITED (GB) | 2008-11-13 | — | — | WO | disclosed |