Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 5/20 | 0.34 |
| ▸ | TMPRSS6 | Q8IU80 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | WDR5 | P61964 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4748774 | 0.90 | ALDH1A1 (0.43) | STAT3CA12CA1CA2CA9 | |
| SCHEMBL165561 | 0.86 | ALDH1A1 (0.46) | CA12CA1CA2CA9CA14 | |
| SCHEMBL3960465 | 0.79 | ALDH1A1 (0.50) | CA12CA1CA2CA9CA14 | |
| SCHEMBL6577887 | 0.79 | TPMT (0.43) | CA12CA1CA2CA9CA14 | |
| SCHEMBL3403399 | 0.79 | TPMT (0.43) | CA12CA1CA2CA9CA14 | |
| SCHEMBL20894429 | 0.76 | KDM4E (0.47) | CA12CA1CA2CA9CA14 | |
| SCHEMBL25708271 | 0.73 | TPMT (0.57) | CA12CA1CA2CA9CA14 | |
| SCHEMBL4751276 | 0.72 | CA12 (0.38) | STAT3CA12CA1CA2CA9 | |
| SCHEMBL7058435 | 0.72 | CA12 (0.47) | STAT3CA12CA1CA2CA9 | |
| SCHEMBL20928667 | 0.71 | SLC7A5 (0.38) | CA12CA1CA2CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008135488-A1 | ASPARTYL PROTEASE INHIBITORS | MEDIVIR AB (SE) | 2008-11-13 | — | — | WO | disclosed |