Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.60 |
| ▸ | HPGD | P15428 | 5/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.54 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.47 |
| ▸ | PLK1 | P53350 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
| ▸ | FABP4 | P15090 | 1/20 | 0.46 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.45 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.45 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.45 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4811594 | 0.84 | ALDH1A1 (0.57) | ALDH1A1HSD17B10HPGDKDM4EAGTR1 | |
| SCHEMBL647371 | 0.83 | KDM4E (0.67) | ALDH1A1HSD17B10HPGDKDM4EPOLB | |
| SCHEMBL17433851 | 0.83 | FABP4 (0.56) | ALDH1A1HSD17B10HPGDKDM4EAGTR1 | |
| SCHEMBL8689214 | 0.81 | ALDH1A1 (0.79) | ALDH1A1HSD17B10HPGDKDM4EAGTR1 | |
| SCHEMBL5186951 | 0.81 | ALOX15 (0.43) | ALDH1A1HSD17B10HPGDKDM4EPOLB | |
| SCHEMBL2634636 | 0.80 | TSHR (0.60) | ALDH1A1HSD17B10HPGDKDM4EL3MBTL1 | |
| SCHEMBL1902821 | 0.79 | HPGD (0.69) | ALDH1A1HSD17B10HPGDKDM4EAGTR1 | |
| SCHEMBL184136 | 0.78 | ALDH1A1 (0.62) | ALDH1A1HSD17B10HPGDKDM4EAGTR1 | |
| SCHEMBL1170114 | 0.77 | ALDH1A1 (0.67) | ALDH1A1HSD17B10HPGDKDM4EAGTR1 | |
| SCHEMBL29365352 | 0.77 | ALDH1A1 (0.67) | ALDH1A1HSD17B10HPGDKDM4EAGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008135488-A1 | ASPARTYL PROTEASE INHIBITORS | MEDIVIR AB (SE) | 2008-11-13 | — | — | WO | disclosed |