Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4751088 | 1.00 | ALDH1A1 (0.37) | ALDH1A1SMN1; SMN2TDP1TSHRMAPK1 | |
| SCHEMBL3804296 | 0.90 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2TDP1TSHRMAPK1 | |
| SCHEMBL4753551 | 0.88 | ALDH1A1 (0.35) | ALDH1A1SMN1; SMN2TDP1TSHRMAPK1 | |
| SCHEMBL4751352 | 0.88 | ALDH1A1 (0.35) | ALDH1A1SMN1; SMN2TDP1TSHRMAPK1 | |
| SCHEMBL5378987 | 0.85 | SMN1; SMN2 (0.45) | ALDH1A1SMN1; SMN2TDP1TSHRMAPK1 | |
| SCHEMBL5360928 | 0.82 | SMN1; SMN2 (0.54) | ALDH1A1SMN1; SMN2TDP1TSHRMAPK1 | |
| SCHEMBL5363530 | 0.79 | SMN1; SMN2 (0.45) | ALDH1A1SMN1; SMN2TDP1TSHRMAPK1 | |
| SCHEMBL5031053 | 0.79 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2TDP1TSHRMAPK1 | |
| SCHEMBL5026325 | 0.79 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2TDP1TSHRMAPK1 | |
| SCHEMBL4753650 | 0.77 | SMN1; SMN2 (0.50) | ALDH1A1SMN1; SMN2TDP1TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008149375-A1 | IMPROVED ORGANOSILICON COMPOUNDS | RANKA, SEEMA, AJAY (IN) | 2008-12-11 | — | — | WO | claimed |
| US-20080009644-A1 | Organosilicon Compounds | ZYDEX INDUSTRIES | 2008-01-10 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080009644-A1 | Organosilicon Compounds | CUL1, CUL3, MGAM | ALDH1A1 1076/4885SMN1; SMN2 2307/4885TDP1 681/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.