SCHEMBL5360928

SCHEMBL5360928

CCCCO[Si](CC(C)COCC1CO1)(OCCCC)OCCCC

nearest known ligand 0.54

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.54
ALDH1A1 P00352 4/20 0.49
TDP1 Q9NUW8 1/20 0.47
TSHR P16473 2/20 0.40
MAPK1 P28482 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5378987 0.91 SMN1; SMN2 (0.45) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL5371046 0.87 SMN1; SMN2 (0.57) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL3804296 0.85 ALDH1A1 (0.43) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL4751088 0.82 ALDH1A1 (0.37) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL4751377 0.82 ALDH1A1 (0.37) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL5598299 0.79 SMN1; SMN2 (0.57) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL188423 0.79 SMN1; SMN2 (0.49) SMN1; SMN2ALDH1A1TDP1TSHR
SCHEMBL188380 0.79 SMN1; SMN2 (0.65) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL5024824 0.79 ALDH1A1 (0.41) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL5360247 0.78 SMN1; SMN2 (0.47) SMN1; SMN2ALDH1A1TDP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070251448-A1 Application method, applicator, optical member, and optical device SAKURADA KAZUAKI 2007-11-01 US disclosed
US-7250190-B2 Application method, applicator, optical member, and optical device SEIKO EPSON CORPORATION (JP) 2007-07-31 US disclosed
US-6773465-B1 Optical element ITOH OPTICAL INDUSTRIAL CO., LTD. (JP) 2004-08-10 US disclosed
US-20040142105-A1 Application method, applicator, optical member, and optical device SEIKO EPSON CORPORATION (JP) 2004-07-22 US disclosed
US-4294950-A POLYVALENT CARBOXYLIC ACID BONDED THERETO ITO OPTICAL INDUSTRIAL CO., LTD. (JP) 1981-10-13 US disclosed