Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | KDM2B | Q8NHM5 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4751582 | 1.00 | KMT2A (0.46) | KMT2AHTTALDH1A1HSD11B1KDM2B | |
| SCHEMBL4751581 | 1.00 | KMT2A (0.46) | KMT2AHTTALDH1A1HSD11B1KDM2B | |
| SCHEMBL4022793 | 0.92 | KMT2A (0.43) | KMT2AHTTALDH1A1HSD11B1KDM2B | |
| SCHEMBL4022795 | 0.92 | KMT2A (0.43) | KMT2AHTTALDH1A1HSD11B1KDM2B | |
| SCHEMBL4022254 | 0.91 | SMN1; SMN2 (0.45) | KMT2AHTTALDH1A1HSD11B1KDM2B | |
| SCHEMBL13721371 | 0.91 | SMN1; SMN2 (0.45) | KMT2AHTTALDH1A1HSD11B1KDM2B | |
| SCHEMBL4022259 | 0.91 | SMN1; SMN2 (0.45) | KMT2AHTTALDH1A1HSD11B1KDM2B | |
| SCHEMBL4025311 | 0.86 | HSD11B1 (0.41) | KMT2AHTTALDH1A1HSD11B1KDM2B | |
| SCHEMBL4025306 | 0.86 | HSD11B1 (0.41) | KMT2AHTTALDH1A1HSD11B1KDM2B | |
| SCHEMBL4023656 | 0.86 | MGLL (0.38) | KMT2AALDH1A1MEN1MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008140810-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INCORPORATED (US) | 2008-11-20 | — | — | WO | claimed |
| WO-2008140810-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INCORPORATED (US) | 2008-11-20 | — | — | WO | disclosed |