Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
| ▸ | ESRRA | P11474 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.34 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | XDH | P47989 | 1/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4751606 | 0.84 | PGR (0.44) | ARMRGPRX4ESRRA | |
| SCHEMBL24074650 | 0.79 | AR (0.46) | ARMRGPRX4TDP1CYP11B2XDH | |
| SCHEMBL4751285 | 0.77 | ALDH1A1 (0.32) | DPP4KCNH2 | |
| SCHEMBL28338571 | 0.71 | AR (0.45) | ARMRGPRX4ESRRAUSP30S1PR3 | |
| SCHEMBL18621197 | 0.71 | AR (0.45) | ARMRGPRX4S1PR3 | |
| SCHEMBL16483388 | 0.68 | AR (0.48) | ARMRGPRX4 | |
| SCHEMBL14022463 | 0.68 | RAB9A (0.65) | ARMRGPRX4NPC1RAB9AUSP30 | |
| SCHEMBL21237872 | 0.68 | ATM (0.53) | ARMRGPRX4NPC1RAB9ATDP1 | |
| SCHEMBL509379 | 0.67 | AR (0.50) | ARMRGPRX4NPC1RAB9A | |
| SCHEMBL14553122 | 0.67 | AR (0.47) | ARMRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008135824-A1 | OXYALKYLPYRAZOLE COMPOUNDS USEFUL IN THERAPY | PFIZER LIMITED (GB) | 2008-11-13 | — | — | WO | disclosed |