Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NOS3 | P29474 | 1/20 | 0.44 |
| ▸ | NOS1 | P29475 | 1/20 | 0.44 |
| ▸ | NOS2 | P35228 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | BRD4 | O60885 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL985894 | 0.87 | NOS3 (0.44) | MAPTALDH1A1NPSR1MEN1MAPK1 | |
| SCHEMBL1425864 | 0.87 | KDM4E (0.46) | MAPTALDH1A1NPSR1MEN1MAPK1 | |
| SCHEMBL1425950 | 0.76 | HTR2C (0.38) | MAPTALDH1A1MEN1KMT2ANOS3 | |
| SCHEMBL3003136 | 0.73 | NOS3 (0.46) | MAPTALDH1A1NPSR1MEN1RAB9A | |
| SCHEMBL4440748 | 0.73 | NOS3 (0.35) | MAPTALDH1A1MEN1MAPK1RAB9A | |
| SCHEMBL985531 | 0.73 | PIN1 (0.41) | MAPTALDH1A1NPSR1MEN1RAB9A | |
| SCHEMBL2840999 | 0.72 | KMT2A (0.43) | MAPTALDH1A1NPSR1MEN1MAPK1 | |
| SCHEMBL2383675 | 0.72 | HSD17B10 (0.36) | MAPTALDH1A1NPSR1MEN1MAPK1 | |
| SCHEMBL22231063 | 0.72 | KMT2A (0.43) | MAPTALDH1A1NPSR1MEN1MAPK1 | |
| SCHEMBL1182615 | 0.72 | SMN1; SMN2 (0.42) | MAPTALDH1A1NPSR1MEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008135526-A1 | CARBOXYLIC ACID AMIDES AS FACTOR XA INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-11-13 | — | — | WO | disclosed |