Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TACR1 | P25103 | 1/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4752003 | 0.92 | BCHE (0.34) | SCN9AKDM2BACHEMEN1KMT2A | |
| SCHEMBL4019044 | 0.92 | BCHE (0.34) | SCN9AKDM2BACHEMEN1KMT2A | |
| SCHEMBL4752006 | 0.92 | BCHE (0.34) | SCN9AKDM2BACHEMEN1KMT2A | |
| SCHEMBL4751838 | 0.91 | KIF11 (0.34) | SCN9AACHE | |
| SCHEMBL4749467 | 0.91 | KIF11 (0.34) | SCN9AACHE | |
| SCHEMBL4751839 | 0.91 | KIF11 (0.34) | SCN9AACHE | |
| SCHEMBL4749435 | 0.91 | KIF11 (0.34) | SCN9AACHE | |
| SCHEMBL4749462 | 0.91 | KIF11 (0.34) | SCN9AACHE | |
| SCHEMBL4749135 | 0.89 | SLC6A5 (0.32) | SCN9AKDM2BACHEMEN1KMT2A | |
| SCHEMBL4028516 | 0.87 | BCHE (0.35) | SCN9AKDM2BMEN1KMT2ATACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008140810-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INCORPORATED (US) | 2008-11-20 | — | — | WO | disclosed |