SCHEMBL4751699

SCHEMBL4751699

Nc1cc(C[C@H]2C(=O)N(C(=O)Nc3ccccc3)[C@@H]2C(=O)O)ccn1

nearest known ligand 0.62

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
F11 P03951 16/20 0.62
TPSAB1 Q15661 4/20 0.53
TPSD1 Q9BZJ3 4/20 0.53
TPSG1 Q9NRR2 4/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13302756 1.00 F11 (0.62) F11TPSAB1TPSD1TPSG1
Trifluoroacetic Acid SCHEMBL3334678 0.94 F11 (0.56) F11TPSAB1TPSD1TPSG1
Trifluoroacetic Acid SCHEMBL3330678 0.94 F11 (0.56) F11TPSAB1TPSD1TPSG1
SCHEMBL16997904 0.86 F11 (0.61) F11TPSAB1TPSD1TPSG1
SCHEMBL20901354 0.86 F11 (0.61) F11TPSAB1TPSD1TPSG1
SCHEMBL27045904 0.86 F11 (0.61) F11TPSAB1TPSD1TPSG1
SCHEMBL16997636 0.86 F11 (0.68) F11TPSAB1TPSD1TPSG1
SCHEMBL3337207 0.85 F11 (0.48) F11TPSAB1TPSD1TPSG1
SCHEMBL3330683 0.85 F11 (0.48) F11TPSAB1TPSD1TPSG1
SCHEMBL13801437 0.85 F11 (0.67) F11TPSAB1TPSD1TPSG1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100144698-A1 SUBSTITUTED AZETIDINONES DAIAMED (US) 2010-06-10 US disclosed
US-20090143351-A1 SUBSTITUTED AZETIDINONES DAIAMED (US) 2009-06-04 US disclosed
US-7501404-B2 Substituted azetidinones DAIMED (US) 2009-03-10 US disclosed
US-7501404-B2 Substituted azetidinones DAIMED (US) 2009-03-10 US disclosed
EP-1871741-A2 SUBSTITUTED AZETIDINONES Daiamed, Inc. (US) 2008-01-02 EP disclosed
US-20070105832-A1 Substituted azetidinones Cadrenal Therapeutics, Inc. 2007-05-10 US disclosed
US-20070105832-A1 Substituted azetidinones Cadrenal Therapeutics, Inc. 2007-05-10 US disclosed
WO-2006108039-A2 SUBSTITUTED AZETIDINONES DAIAMED, INC. (US) 2006-10-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070105832-A1 Substituted azetidinones F2R, CPA3, CFD F11 17/4885TPSAB1 14/4885TPSD1 24/4885
US-20100144698-A1 SUBSTITUTED AZETIDINONES F2R, CPA3, CFD F11 17/4885TPSAB1 14/4885TPSD1 24/4885
US-20090143351-A1 SUBSTITUTED AZETIDINONES F2R, CPA3, CFD F11 17/4885TPSAB1 14/4885TPSD1 24/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.