Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 4/20 | 0.44 |
| ▸ | ENPEP | Q07075 | 3/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.42 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 2/20 | 0.40 |
| ▸ | CES1 | P23141 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | FNTA | P49354 | 2/20 | 0.40 |
| ▸ | FNTB | P49356 | 2/20 | 0.40 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.40 |
| ▸ | ALPI | P09923 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | XIAP | P98170 | 1/20 | 0.39 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.39 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14227029 | 0.93 | ANPEP (0.49) | ANPEPENPEPPTGS1SLC7A11MMP2 | |
| SCHEMBL16330499 | 0.93 | ANPEP (0.49) | ANPEPENPEPPTGS1SLC7A11MMP2 | |
| SCHEMBL5495906 | 0.84 | MDM2 (0.43) | PTGS1MDM2TDP1L3MBTL1CES2 | |
| SCHEMBL14843883 | 0.81 | KMO (0.40) | ANPEPENPEPCES2CES1FNTA | |
| SCHEMBL1969120 | 0.81 | L3MBTL1 (0.41) | PTGS1MDM2TDP1L3MBTL1CES2 | |
| SCHEMBL5057390 | 0.81 | MDM2 (0.41) | PTGS1MDM2TDP1L3MBTL1CES2 | |
| SCHEMBL2574988 | 0.79 | PDPK1 (0.46) | ANPEPENPEPPTGS1SLC7A11TDP1 | |
| SCHEMBL2574989 | 0.79 | PDPK1 (0.46) | ANPEPENPEPPTGS1SLC7A11TDP1 | |
| SCHEMBL1970885 | 0.78 | BLM (0.47) | PTGS1MMP2MDM2TDP1L3MBTL1 | |
| SCHEMBL5034524 | 0.77 | MDM2 (0.47) | PTGS1MDM2TDP1L3MBTL1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008137165-A1 | ANTI-GLYCATED CD59 ANTIBODIES AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2008-11-13 | — | — | WO | disclosed |