Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 9/20 | 0.53 |
| ▸ | DRD2 | P14416 | 8/20 | 0.53 |
| ▸ | DRD3 | P35462 | 7/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL885809 | 0.83 | OPRM1 (0.47) | DRD4DRD2DRD3ALDH1A1TSHR | |
| SCHEMBL7169413 | 0.73 | TDP1 (0.60) | ALDH1A1TSHRMAPK1POLBGAA | |
| SCHEMBL9894423 | 0.73 | MAPT (0.54) | ALDH1A1TSHRMAPK1OPRM1OPRD1 | |
| SCHEMBL25360981 | 0.71 | ALDH1A1 (0.45) | ALDH1A1TSHRMAPK1OPRM1OPRD1 | |
| SCHEMBL4281769 | 0.70 | OGFRL1 (0.53) | ALDH1A1TSHROPRM1OPRD1OPRK1 | |
| SCHEMBL4284918 | 0.70 | OGFRL1 (0.53) | ALDH1A1TSHROPRM1OPRD1OPRK1 | |
| SCHEMBL1260403 | 0.70 | ALDH1A1 (0.49) | ALDH1A1MAPK1OPRM1OPRD1OPRK1 | |
| SCHEMBL885834 | 0.69 | MEN1 (0.46) | DRD4DRD2DRD3ALDH1A1MAPK1 | |
| SCHEMBL9642259 | 0.69 | DRD2 (0.64) | DRD4DRD2DRD3ALDH1A1MAPK1 | |
| SCHEMBL8689759 | 0.68 | SMN1; SMN2 (0.41) | MAPK1HTTGAACHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008139941-A1 | SUBSTITUTED IMIDAZOLE COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-11-20 | — | — | WO | disclosed |