Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.45 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.45 |
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | PLD1 | Q13393 | 3/20 | 0.41 |
| ▸ | PLD2 | O14939 | 2/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4752476 | 0.76 | SLC6A2 (0.40) | ALDH1A1HPGD | |
| SCHEMBL30838374 | 0.73 | POLB (1.00) | POLBDAOALDH1A1HPGDMEN1 | |
| SCHEMBL828232 | 0.73 | POLB (1.00) | POLBDAOALDH1A1HPGDMEN1 | |
| SCHEMBL4753544 | 0.71 | CHRM2 (0.37) | POLBCHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL904825 | 0.70 | POLB (0.74) | POLBDAOOPRM1ALDH1A1HPGD | |
| SCHEMBL7017890 | 0.70 | POLB (0.74) | POLBDAOOPRM1ALDH1A1HPGD | |
| SCHEMBL10736441 | 0.70 | POLB (0.74) | POLBDAOOPRM1ALDH1A1HPGD | |
| SCHEMBL23997201 | 0.70 | POLB (0.68) | POLBDAOALDH1A1HPGDMEN1 | |
| SCHEMBL30336952 | 0.70 | POLB (0.68) | POLBDAOALDH1A1HPGDMEN1 | |
| SCHEMBL7513143 | 0.70 | POLB (0.68) | POLBDAOPLD1OPRM1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008139941-A1 | SUBSTITUTED IMIDAZOLE COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-11-20 | — | — | WO | disclosed |