Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | DTYMK | P23919 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2270985 | 0.75 | TP53 (0.46) | POLBPARP1L3MBTL1ALDH1A1GAA | |
| SCHEMBL30056795 | 0.75 | TP53 (0.46) | POLBPARP1L3MBTL1ALDH1A1GAA | |
| SCHEMBL20725319 | 0.73 | KDM4E (0.44) | POLBPARP1L3MBTL1ALDH1A1GAA | |
| SCHEMBL3894139 | 0.71 | SMN1; SMN2 (0.41) | POLBPARP1L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL4752572 | 0.71 | POLB (0.56) | CHRM2CHRM4CHRM1CHRM3POLB | |
| SCHEMBL4752476 | 0.70 | SLC6A2 (0.40) | ALDH1A1GAAKDM4EHPGDMAPK1 | |
| SCHEMBL4752313 | 0.67 | HSD17B10 (0.50) | POLBL3MBTL1ALDH1A1KDM4ERAB9A | |
| SCHEMBL4303680 | 0.67 | HSD17B10 (0.47) | POLBALDH1A1GAARAB9AHSD17B10 | |
| SCHEMBL4749932 | 0.67 | KMT2A (0.48) | POLBHPGDSMN1; SMN2HSD17B10MEN1 | |
| SCHEMBL22605851 | 0.64 | PRKCG (0.54) | CHRM2CHRM4CHRM1CHRM3PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008139941-A1 | SUBSTITUTED IMIDAZOLE COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-11-20 | — | — | WO | disclosed |