Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4752572 | 0.76 | POLB (0.56) | ALDH1A1HPGD | |
| SCHEMBL12139324 | 0.71 | SLC6A2 (0.50) | SLC6A2SMN1; SMN2ALDH1A1HTR4BRD4 | |
| SCHEMBL4753544 | 0.70 | CHRM2 (0.37) | MAPK1SMN1; SMN2KDM4EALDH1A1HPGD | |
| SCHEMBL27264999 | 0.69 | SLC6A2 (0.48) | SLC6A2SMN1; SMN2ALDH1A1BRD4BRPF1 | |
| SCHEMBL4749932 | 0.69 | KMT2A (0.48) | SMN1; SMN2HPGDHSD17B10 | |
| SCHEMBL4303680 | 0.69 | HSD17B10 (0.47) | ALDH1A1HSD17B10GAA | |
| SCHEMBL4752313 | 0.69 | HSD17B10 (0.50) | SMN1; SMN2KDM4EALDH1A1HSD17B10 | |
| SCHEMBL29311531 | 0.66 | SLC6A2 (0.49) | SLC6A2KDM4EALDH1A1HPGDGAA | |
| SCHEMBL29798837 | 0.65 | CYP1A2 (0.55) | SMN1; SMN2KDM4EALDH1A1HSD17B10BRD4 | |
| SCHEMBL474339 | 0.65 | CYP1A2 (0.55) | SMN1; SMN2KDM4EALDH1A1HSD17B10BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008139941-A1 | SUBSTITUTED IMIDAZOLE COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-11-20 | — | — | WO | disclosed |