Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | DAO | P14920 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.33 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | RAD52 | P43351 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.30 |
| ▸ | THPO | P40225 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3310259 | 1.00 | ALDH1A1 (0.37) | ALDH1A1DAOSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3307455 | 0.91 | HPGD (0.40) | ALDH1A1SLC6A2SLC6A4SLC6A3KDM4E | |
| SCHEMBL4749337 | 0.86 | ALDH1A1 (0.36) | ALDH1A1DAOTBXAS1KDM4EMAPT | |
| SCHEMBL4751673 | 0.82 | ALDH1A1 (0.40) | ALDH1A1DAOTBXAS1KDM4EMAPT | |
| SCHEMBL4435809 | 0.82 | SLC6A2 (0.32) | SLC6A2SLC6A4SLC6A3CYP3A4CYP2D6 | |
| SCHEMBL4748908 | 0.79 | DRD1 (0.33) | SLC6A2SLC6A4SLC6A3KDM4ECYP3A4 | |
| SCHEMBL3308477 | 0.79 | DRD1 (0.33) | SLC6A2SLC6A4SLC6A3KDM4ECYP3A4 | |
| SCHEMBL4748891 | 0.79 | KDM4E (0.37) | ALDH1A1DAOTBXAS1KDM4EMAPT | |
| SCHEMBL4748892 | 0.79 | KDM4E (0.37) | ALDH1A1DAOTBXAS1KDM4EMAPT | |
| SCHEMBL4431719 | 0.79 | SLC6A2 (0.31) | SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008135526-A1 | CARBOXYLIC ACID AMIDES AS FACTOR XA INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-11-13 | — | — | WO | disclosed |