Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 13/20 | 0.46 |
| ▸ | DRD4 | P21917 | 10/20 | 0.46 |
| ▸ | CCR3 | P51677 | 2/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4749499 | 0.99 | DRD2 (0.45) | DRD2DRD4CCR3DRD3DYRK1A | |
| SCHEMBL13721566 | 0.95 | DRD4 (0.42) | DRD2DRD4CCR3 | |
| SCHEMBL4022160 | 0.95 | DRD4 (0.42) | DRD2DRD4CCR3 | |
| SCHEMBL4022167 | 0.95 | DRD4 (0.42) | DRD2DRD4CCR3 | |
| SCHEMBL4751954 | 0.88 | DRD4 (0.44) | DRD2DRD4CCR3DRD3 | |
| SCHEMBL13720836 | 0.87 | SMN1; SMN2 (0.37) | DRD2DRD4 | |
| SCHEMBL4021768 | 0.87 | SMN1; SMN2 (0.37) | DRD2DRD4 | |
| SCHEMBL4021763 | 0.87 | SMN1; SMN2 (0.37) | DRD2DRD4 | |
| SCHEMBL4025349 | 0.87 | DRD4 (0.43) | DRD2DRD4CCR3DRD3 | |
| SCHEMBL4022832 | 0.85 | KDM2B (0.43) | DRD2DRD4CCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008140810-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INCORPORATED (US) | 2008-11-20 | — | — | WO | claimed |
| WO-2008140810-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INCORPORATED (US) | 2008-11-20 | — | — | WO | disclosed |