Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ILK | Q13418 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5578040 | 0.81 | DYRK1A (0.32) | — | |
| SCHEMBL3500615 | 0.77 | ALDH1A1 (0.31) | — | |
| SCHEMBL3501102 | 0.73 | CYP1A2 (0.43) | — | |
| SCHEMBL4752792 | 0.72 | RPS6KA3 (0.47) | — | |
| SCHEMBL3498258 | 0.70 | LRRK2 (0.40) | — | |
| SCHEMBL3501617 | 0.70 | GRM2 (0.38) | — | |
| SCHEMBL18572797 | 0.68 | LCK (0.46) | — | |
| SCHEMBL5577976 | 0.68 | CYP1A2 (0.36) | — | |
| SCHEMBL14454809 | 0.66 | NPC1 (0.52) | — | |
| SCHEMBL5577853 | 0.65 | SMN1; SMN2 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1966222-A2 | PYRAZOLOTHIAZOLE PROTEIN KINASE MODULATORS | SGX Pharmaceuticals, Inc. (US) | 2008-09-10 | — | — | EP | disclosed |
| US-20070173488-A1 | Pyrazolothiazole Protein Kinase Modulators | SGX PHARMACEUTICALS, INC. (US) | 2007-07-26 | — | — | US | disclosed |
| WO-2007059341-A2 | PYRAZOLOTHIAZOLE PROTEIN KINASE MODULATORS | SGX PHARMACEUTICALS, INC. (US) | 2007-05-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070173488-A1 | Pyrazolothiazole Protein Kinase Modulators | MAP4K2, MAP4K5, MAP4K3 | ILK 710/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.