Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4752790 | 0.81 | ILK (0.32) | — | |
| SCHEMBL3500615 | 0.76 | ALDH1A1 (0.31) | — | |
| SCHEMBL3501617 | 0.74 | GRM2 (0.38) | DYRK1ADYRK1B | |
| SCHEMBL3501102 | 0.72 | CYP1A2 (0.43) | — | |
| SCHEMBL14454810 | 0.67 | KMT2A (0.49) | — | |
| SCHEMBL5577976 | 0.67 | CYP1A2 (0.36) | DYRK1A | |
| SCHEMBL18549579 | 0.62 | SMN1; SMN2 (0.35) | — | |
| SCHEMBL18555195 | 0.62 | AURKA (0.40) | DYRK1ADYRK1B | |
| SCHEMBL16751925 | 0.61 | ALDH1A1 (0.34) | DYRK1ADYRK1B | |
| SCHEMBL473007 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070173488-A1 | Pyrazolothiazole Protein Kinase Modulators | SGX PHARMACEUTICALS, INC. (US) | 2007-07-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070173488-A1 | Pyrazolothiazole Protein Kinase Modulators | MAP4K2, MAP4K5, MAP4K3 | DYRK1A 577/4885DYRK1B 585/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.