Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 2/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.34 |
| ▸ | OXTR | P30559 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 9/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 9/20 | 0.33 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 4/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4752708 | 0.84 | MEN1 (0.43) | TAAR1CYP2D6HCRTR1HCRTR2RIPK1 | |
| SCHEMBL4749426 | 0.82 | EED (0.42) | TAAR1CYP2D6RIPK1 | |
| SCHEMBL4749424 | 0.82 | EED (0.42) | TAAR1CYP2D6RIPK1 | |
| SCHEMBL4749432 | 0.79 | CYP2D6 (0.34) | TAAR1CYP2D6HCRTR1HCRTR2 | |
| SCHEMBL4749407 | 0.74 | EED (0.32) | RIPK1 | |
| SCHEMBL4023587 | 0.72 | EED (0.41) | — | |
| SCHEMBL4023583 | 0.72 | EED (0.41) | — | |
| SCHEMBL4026176 | 0.70 | KMT2A (0.39) | TAAR1CYP2D6HCRTR1HCRTR2 | |
| SCHEMBL4019575 | 0.69 | EED (0.37) | TAAR1CYP2D6PROKR1 | |
| SCHEMBL4019577 | 0.69 | EED (0.37) | TAAR1CYP2D6PROKR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008140810-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INCORPORATED (US) | 2008-11-20 | — | — | WO | disclosed |