Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4752838 | 1.00 | OPRM1 (0.32) | OPRM1OPRD1OPRK1KDM2BMGLL | |
| SCHEMBL4020419 | 0.91 | KDM2B (0.32) | OPRM1OPRD1OPRK1KDM2BMGLL | |
| SCHEMBL4018647 | 0.86 | KDM2B (0.33) | KDM2BMGLL | |
| SCHEMBL4020603 | 0.85 | KDM2B (0.33) | OPRM1OPRK1KDM2BMGLL | |
| SCHEMBL13721304 | 0.84 | KDM2B (0.34) | KDM2BMGLL | |
| SCHEMBL4023878 | 0.84 | KDM2B (0.34) | KDM2BMGLL | |
| SCHEMBL4022530 | 0.84 | KDM2B (0.34) | KDM2BMGLL | |
| SCHEMBL4025503 | 0.84 | KIF11 (0.34) | OPRM1OPRD1OPRK1KDM2BMGLL | |
| SCHEMBL4749198 | 0.83 | MEN1 (0.33) | KDM2BMGLL | |
| SCHEMBL4749185 | 0.82 | KDM2B (0.31) | OPRM1OPRD1OPRK1KDM2BMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008140810-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INCORPORATED (US) | 2008-11-20 | — | — | WO | claimed |
| WO-2008140810-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INCORPORATED (US) | 2008-11-20 | — | — | WO | disclosed |