SCHEMBL4752952

SCHEMBL4752952

O=C1N=Nc2cccc([N+](=O)[O-])c21

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
S100A4 P26447 2/20 0.52
TDP1 Q9NUW8 2/20 0.48
PTPRC P08575 1/20 0.47
MAPT P10636 1/20 0.46
RECQL P46063 1/20 0.46
KMT2A Q03164 1/20 0.46
MCL1 Q07820 1/20 0.46
RXFP1 Q9HBX9 1/20 0.46
GPR35 Q9HC97 2/20 0.44
ACHE P22303 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA7 P43166 1/20 0.44
CA9 Q16790 1/20 0.44
HSD17B10 Q99714 1/20 0.42
KDM4E B2RXH2 1/20 0.41
CYP1A2 P05177 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8979627 0.81 S100A4 (0.61) S100A4TDP1PTPRCMAPTRECQL
SCHEMBL3039191 0.75 TDP1 (0.67) S100A4TDP1PTPRCMAPTRECQL
SCHEMBL244916 0.70 S100A4 (0.61) S100A4TDP1PTPRCMAPTRECQL
SCHEMBL31272464 0.69 S100A4 (0.50) S100A4TDP1PTPRCMAPTRECQL
SCHEMBL1611362 0.69 S100A4 (0.50) S100A4TDP1PTPRCMAPTRECQL
SCHEMBL2599501 0.68 S100A4 (1.00) S100A4TDP1PTPRCMAPTRECQL
SCHEMBL28651375 0.68 S100A4 (0.92) S100A4TDP1PTPRCMAPTRECQL
SCHEMBL2347136 0.68 S100A4 (0.84) S100A4TDP1PTPRCMAPTRECQL
SCHEMBL9257330 0.68 S100A4 (0.77) S100A4TDP1PTPRCMAPTRECQL
SCHEMBL407275 0.68 TDP1 (0.47) S100A4TDP1MAPTRECQLKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1994002116-A1 NITROINDAZOLINONES AS COLORANTS FOR NATURAL AND SYNTHETIC FIBRES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1994-02-03 WO claimed
WO-2008141385-A1 VIRAL POLYMERASE INHIBITORS BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) 2008-11-27 WO disclosed
WO-1994002116-A1 NITROINDAZOLINONES AS COLORANTS FOR NATURAL AND SYNTHETIC FIBRES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1994-02-03 WO disclosed
WO-1994002116-A1 NITROINDAZOLINONES AS COLORANTS FOR NATURAL AND SYNTHETIC FIBRES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1994-02-03 WO disclosed