Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 5/20 | 0.34 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.33 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8612010 | 0.75 | SMN1; SMN2 (0.33) | CYP1A2CYP2A6TSHRALDH1A1 | |
| SCHEMBL6993650 | 0.60 | CYP1A2 (0.44) | AHRPSMB8PSMB5CYP1A2CYP2A6 | |
| SCHEMBL9345812 | 0.60 | NOS1 (0.39) | AHRPSMB8PSMB5CYP1A2CYP2A6 | |
| SCHEMBL9479816 | 0.58 | CYP1A2 (0.42) | CYP1A2CYP2A6LMNATSHRNR4A2 | |
| SCHEMBL2437835 | 0.58 | NOS1 (0.42) | AHRPSMB8CYP1A2CYP2A6LMNA | |
| SCHEMBL208222 | 0.58 | AHR (0.37) | AHRPSMB8CYP1A2LMNATSHR | |
| SCHEMBL940307 | 0.58 | PSMB8 (0.41) | AHRPSMB8PSMB5CYP1A2CYP2A6 | |
| SCHEMBL28617099 | 0.58 | AHR (0.69) | AHRPSMB8PSMB5CYP1A2CYP2A6 | |
| SCHEMBL20870713 | 0.57 | LMNA (0.47) | AHRPSMB8PSMB5CYP1A2CYP2A6 | |
| SCHEMBL482230 | 0.57 | NR4A2 (0.47) | AHRPSMB8PSMB5CYP1A2CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008146064-A1 | NEW BENZOFURAN DERIVATIVES AS SELECTIVE 5HT7 RECEPTOR INHIBITORS AND PROCESS FOR THEIR PREPARATION | EGIS GYÓGYSZERGYÁR (HU) | 2008-12-04 | — | — | WO | disclosed |