Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 3/20 | 0.37 |
| ▸ | HTR5A | P47898 | 1/20 | 0.35 |
| ▸ | PBRM1 | Q86U86 | 3/20 | 0.35 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.35 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.35 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 3/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA7 | P43166 | 2/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | DDO | Q99489 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6587215 | 0.76 | PLAUR (0.31) | — | |
| SCHEMBL4750499 | 0.76 | CES1 (0.44) | PARP1HTR5APBRM1LRRK2DAO | |
| SCHEMBL6230711 | 0.76 | MEN1 (0.37) | PARP1CA9CA12CA1CA2 | |
| SCHEMBL6120237 | 0.76 | PARP1 (0.33) | PARP1 | |
| SCHEMBL4752467 | 0.76 | CES1 (0.41) | PARP1AR | |
| SCHEMBL5132320 | 0.72 | TDP1 (0.44) | PARP1NOS3NOS1NOS2CA9 | |
| SCHEMBL3159742 | 0.72 | TDP1 (0.44) | PARP1NOS3NOS1NOS2CA9 | |
| SCHEMBL3741907 | 0.68 | — | — | |
| SCHEMBL4750823 | 0.68 | CA9 (0.40) | PARP1HTR5AARDDB1CRBN | |
| SCHEMBL20505096 | 0.66 | MAPT (0.44) | NPC1LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008146064-A1 | NEW BENZOFURAN DERIVATIVES AS SELECTIVE 5HT7 RECEPTOR INHIBITORS AND PROCESS FOR THEIR PREPARATION | EGIS GYÓGYSZERGYÁR (HU) | 2008-12-04 | — | — | WO | disclosed |