Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAUR | Q03405 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6230711 | 0.76 | MEN1 (0.37) | — | |
| SCHEMBL4750499 | 0.76 | CES1 (0.44) | — | |
| SCHEMBL4752983 | 0.76 | PARP1 (0.37) | — | |
| SCHEMBL6120237 | 0.76 | PARP1 (0.33) | — | |
| SCHEMBL3741907 | 0.72 | — | — | |
| SCHEMBL5132320 | 0.72 | TDP1 (0.44) | — | |
| SCHEMBL20505096 | 0.66 | MAPT (0.44) | — | |
| SCHEMBL20723 | 0.66 | MAPT (0.44) | — | |
| SCHEMBL2009663 | 0.65 | LMNA (0.30) | — | |
| SCHEMBL25800020 | 0.63 | NPC1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1458712-A2 | NOVEL COMPOUNDS | AstraZeneca AB (SE) | 2004-09-22 | — | — | EP | disclosed |
| WO-2003051277-A2 | NOVEL COMPOUNDS | ASTRAZENECA AB (SE) | 2003-06-26 | — | — | WO | disclosed |