Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | BCL9 | O00512 | 1/20 | 0.38 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6820152 | 0.81 | HTR2A (0.51) | HTR2AMEN1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL4754617 | 0.75 | SMN1; SMN2 (0.46) | HTR2AMEN1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL23922808 | 0.75 | HTR2A (0.54) | HTR2AMEN1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL21097214 | 0.75 | HTR2A (0.54) | HTR2AMEN1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL21098056 | 0.75 | HTR2A (0.54) | HTR2AMEN1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL2232985 | 0.73 | ALDH1A1 (0.46) | HTR2AMEN1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL9996323 | 0.73 | MGLL (0.44) | MEN1KMT2ACYP1A2CYP2D6SMN1; SMN2 | |
| SCHEMBL2235352 | 0.73 | KMT2A (0.47) | HTR2AMEN1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL12255060 | 0.73 | HTR2A (0.56) | HTR2AMEN1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL7687166 | 0.73 | GAA (0.48) | HTR2AMEN1KMT2ACYP1A2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008156832-A2 | RENIN INHIBITORS | VITAE PHARMACEUTICALS, INC. (US) | 2008-12-24 | — | — | WO | disclosed |