Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | BCL9 | O00512 | 1/20 | 0.41 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.41 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.41 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4753078 | 0.80 | L3MBTL1 (0.43) | SMN1; SMN2L3MBTL1CYP1A2CYP2D6ALDH1A1 | |
| SCHEMBL6397367 | 0.79 | HTR2A (0.49) | SMN1; SMN2L3MBTL1CYP1A2CYP2D6ALDH1A1 | |
| SCHEMBL2993617 | 0.78 | L3MBTL1 (0.41) | SMN1; SMN2L3MBTL1CYP1A2CYP2D6ALDH1A1 | |
| SCHEMBL6820152 | 0.78 | HTR2A (0.51) | SMN1; SMN2L3MBTL1CYP1A2CYP2D6ALDH1A1 | |
| SCHEMBL5017678 | 0.77 | HTR2A (0.50) | SMN1; SMN2CYP1A2CYP2D6ALDH1A1KMT2A | |
| SCHEMBL2162730 | 0.77 | CTSS (0.48) | CYP1A2CYP2D6ALDH1A1MAPT | |
| SCHEMBL12196254 | 0.77 | CTSS (0.48) | CYP1A2CYP2D6ALDH1A1MAPT | |
| SCHEMBL2162724 | 0.77 | CTSS (0.48) | CYP1A2CYP2D6ALDH1A1MAPT | |
| SCHEMBL6820153 | 0.77 | MAPT (0.49) | SMN1; SMN2CYP1A2CYP2D6ALDH1A1KMT2A | |
| SCHEMBL4753079 | 0.75 | HTR2A (0.42) | SMN1; SMN2L3MBTL1CYP1A2CYP2D6KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008156832-A2 | RENIN INHIBITORS | VITAE PHARMACEUTICALS, INC. (US) | 2008-12-24 | — | — | WO | disclosed |