Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.35 |
| ▸ | HTR1A | P08908 | 4/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.35 |
| ▸ | DRD1 | P21728 | 4/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.35 |
| ▸ | DRD3 | P35462 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7436460 | 0.80 | ALDH1A1 (0.41) | ALDH1A1HSD17B10SMN1; SMN2KDM4ELMNA | |
| SCHEMBL4753186 | 0.80 | ALDH1A1 (0.41) | ALDH1A1HSD17B10SMN1; SMN2KDM4ELMNA | |
| SCHEMBL4750501 | 0.77 | ADRA2A (0.44) | ALDH1A1TSHRTDP1L3MBTL1KDM4E | |
| SCHEMBL4754016 | 0.75 | ALDH1A1 (0.46) | ALDH1A1HSD17B10SMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL2761355 | 0.74 | ALDH1A1 (0.52) | ALDH1A1HSD17B10SMN1; SMN2TSHRL3MBTL1 | |
| SCHEMBL5544626 | 0.73 | ALDH1A1 (0.53) | ALDH1A1PTGS1KMT2APTGS2 | |
| SCHEMBL4813307 | 0.73 | SMN1; SMN2 (0.38) | ALDH1A1SMN1; SMN2TDP1L3MBTL1KDM4E | |
| SCHEMBL299642 | 0.72 | CASP3 (0.44) | ALDH1A1TSHRTDP1L3MBTL1KDM4E | |
| SCHEMBL5547622 | 0.72 | CDC25A (0.54) | ALDH1A1PTGS1KMT2APTGS2 | |
| SCHEMBL8185591 | 0.71 | SLC9A1 (0.35) | ALDH1A1SMN1; SMN2L3MBTL1PKMHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008146064-A1 | NEW BENZOFURAN DERIVATIVES AS SELECTIVE 5HT7 RECEPTOR INHIBITORS AND PROCESS FOR THEIR PREPARATION | EGIS GYÓGYSZERGYÁR (HU) | 2008-12-04 | — | — | WO | disclosed |