SCHEMBL475319

SCHEMBL475319

COC(OC)c1ccccc1C(C)(C)C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.41
TDP1 Q9NUW8 2/20 0.41
TSHR P16473 2/20 0.41
CA2 P00918 2/20 0.38
GABRA1 P14867 1/20 0.33
GABRB2 P47870 1/20 0.33
LPAR1 Q92633 1/20 0.33
KIF11 P52732 1/20 0.32
MAPT P10636 1/20 0.32
CYP2C19 P33261 3/20 0.32
CYP3A4 P08684 2/20 0.32
ATM Q13315 1/20 0.32
ESR1 P03372 1/20 0.31
CYP1A2 P05177 2/20 0.31
CYP2D6 P10635 1/20 0.31
HSD17B10 Q99714 1/20 0.31
CYP2C9 P11712 1/20 0.30
CRHBP P24387 1/20 0.30
CRHR2 Q13324 1/20 0.30
SLC6A2 P23975 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17864869 0.78 ESR1 (0.40) ALDH1A1TDP1TSHRCA2GABRA1
SCHEMBL9621326 0.75 TSHR (0.46) ALDH1A1TDP1TSHRCA2GABRA1
SCHEMBL4667743 0.75 GABRA1 (0.46) ALDH1A1TDP1TSHRCA2GABRA1
SCHEMBL7941102 0.75 ALDH1A1 (0.52) ALDH1A1TDP1TSHRCA2GABRA1
SCHEMBL29414888 0.75 GABRA1 (0.46) ALDH1A1TDP1TSHRCA2GABRA1
SCHEMBL1679119 0.74 ALDH1A1 (0.34) ALDH1A1CA2
Methoxymethane SCHEMBL28022478 0.73 ALDH1A1 (0.55) ALDH1A1TDP1TSHRCA2GABRA1
SCHEMBL271789 0.73 ALDH1A1 (0.44) ALDH1A1TDP1TSHRCA2GABRA1
SCHEMBL10170299 0.73 ALDH1A1 (0.44) ALDH1A1TDP1TSHRCA2GABRA1
SCHEMBL6258936 0.72 MAPT (0.48) ALDH1A1TDP1CA2GABRA1GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2616424-B1 METHOD FOR PRODUCING 2-METHYL-3-(4-TERT-BUTYLPHENYL)-PROPANAL HAVING HIGH PARA-ISOMER PURITY BASF SE (DE) 2015-08-26 EP disclosed
CN-102365393-B Electrochemical method for producing 3 tert.-butyl benzaldehyde- dimethylacetal BASF SE (DE) 2014-10-29 CN disclosed
CN-102365393-B Electrochemical method for producing 3 tert.-butyl benzaldehyde- dimethylacetal BASF SE (DE) 2014-10-29 CN disclosed
US-8614358-B2 Process for preparing 2-methyl-3-(4-tert-butylphenyl)propanal with high para-isomer purity BASF SE (DE) 2013-12-24 US disclosed
EP-2616424-A1 METHOD FOR PRODUCING 2-METHYL-3-(4-TERT-BUTYLPHENYL)-PROPANAL HAVING HIGH PARA-ISOMER PURITY BASF SE (DE) 2013-07-24 EP disclosed
US-20120071696-A1 PROCESS FOR PREPARING 2-METHYL-3-(4-TERT-BUTYLPHENYL)PROPANAL WITH HIGH PARA-ISOMER PURITY BASF SE (DE) 2012-03-22 US disclosed
WO-2012034930-A1 METHOD FOR PRODUCING 2-METHYL-3-(4-TERT-BUTYLPHENYL)-PROPANAL HAVING HIGH PARA-ISOMER PURITY BASF SE (DE) 2012-03-22 WO disclosed
CN-102365393-A Electrochemical method for producing 3 tert.-butyl benzaldehyde- dimethylacetal BASF SE 2012-02-29 CN disclosed
CN-102365393-A Electrochemical method for producing 3 tert.-butyl benzaldehyde- dimethylacetal BASF SE 2012-02-29 CN disclosed
EP-2411564-A1 ELECTROCHEMICAL METHOD FOR PRODUCING 3 TERT.-BUTYL BENZALDEHYDE- DIMETHYLACETAL BASF SE (DE) 2012-02-01 EP disclosed
WO-2010108874-A1 ELECTROCHEMICAL METHOD FOR PRODUCING 3 TERT.-BUTYL BENZALDEHYDE- DIMETHYLACETAL BASF SE (DE) 2010-09-30 WO disclosed
US-6315884-B1 REDUCING PHTHALIC ACID OR PHTHALIC ACID DERIVATIVES AT CATHODE IN UNDIVIDED ELECTROLYTIC CELL AND DISSOLVED IN ELECTROLYTE; DISCHARGING ELECTROLYTE FROM ELECTROLYTIC CELL; CRYSTALLIZING PHTHALIDES FROM ELECTROLYTE AND REMOVING BASF AKTIENGESELLSCHAFT (DE) 2001-11-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120071696-A1 PROCESS FOR PREPARING 2-METHYL-3-(4-TERT-BUTYLPHENYL)PROPANAL WITH HIGH PARA-ISOMER PURITY HPD, PAH, PTMA ALDH1A1 97/4885TDP1 1353/4885TSHR 2594/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.