Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 1/20 | 0.60 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | CASP7 | P55210 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | AR | P10275 | 1/20 | 0.51 |
| ▸ | PELP1 | Q8IZL8 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31548461 | 0.90 | CASP6 (0.60) | VCAM1SIRT6TDP1LMNAHPGD | |
| SCHEMBL2722165 | 0.90 | CASP6 (0.60) | VCAM1SIRT6TDP1LMNAHPGD | |
| SCHEMBL1353346 | 0.90 | VCAM1 (0.57) | VCAM1SIRT6LMNAHPGDALDH1A1 | |
| SCHEMBL1932039 | 0.89 | SIRT6 (0.53) | VCAM1SIRT6TDP1LMNAALDH1A1 | |
| SCHEMBL30304316 | 0.89 | VCAM1 (0.56) | VCAM1SIRT6TDP1LMNAHPGD | |
| SCHEMBL11330293 | 0.89 | VCAM1 (0.56) | VCAM1SIRT6LMNAHPGDALDH1A1 | |
| SCHEMBL2722007 | 0.88 | VCAM1 (0.56) | VCAM1SIRT6TDP1LMNAHPGD | |
| SCHEMBL19046539 | 0.88 | VCAM1 (0.55) | VCAM1SIRT6LMNAHPGDALDH1A1 | |
| SCHEMBL559830 | 0.87 | VCAM1 (0.64) | VCAM1LMNAHPGDALDH1A1KDM4E | |
| SCHEMBL30525281 | 0.87 | VCAM1 (0.64) | VCAM1LMNAHPGDALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114163400-B | Cyclohexanedione-benzothiadiazine compound and application thereof | 东莞市东阳光农药研发有限公司 | 2025-03-14 | — | — | CN | disclosed |
| CN-218230328-U | Adjustable discharge capacity's receiving tank | 山东沾化万源医化有限公司 | 2023-01-06 | — | — | CN | disclosed |
| CN-114163400-A | Cyclohexanedione-benzothiadiazine compound and application thereof | 东莞市东阳光农药研发有限公司 | 2022-03-11 | — | — | CN | disclosed |
| EP-3190104-B1 | QUINOLINONE COMPOUND AND USE THEREOF | SUNSHINE LAKE PHARMA CO LTD (CN) | 2021-10-27 | — | — | EP | disclosed |
| US-11065343-B2 | Compound bearing beta-galactoside-introduced self-immolative linker | INTOCELL INC. (KR) | 2021-07-20 | — | — | US | disclosed |
| CN-109503556-B | Quinazoline-2, 4-diketone derivative and preparation method and application thereof | 东莞市东阳光农药研发有限公司 | 2020-07-07 | — | — | CN | disclosed |
| US-20190328902-A1 | Compound Bearing Beta-Galactoside-Introduced Self-Immolative Linker | INTOCELL INC. (KR) | 2019-10-31 | — | — | US | disclosed |
| CN-109503556-A | Quinazoline -2,4- derovatives and its preparation method and application | 东莞东阳光科研发有限公司 | 2019-03-22 | — | — | CN | disclosed |
| US-10065928-B2 | Quinolinone compound and use thereof | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2018-09-04 | — | — | US | disclosed |
| EP-3061755-B1 | A TRIKETONE COMPOUND AND PREPARATION METHOD AND USE THEREOF | SHANDONG CYNDA CHEMICAL CO LTD (CN) | 2018-06-27 | — | — | EP | disclosed |
| EP-3061755-A1 | A TRIKETONE COMPOUND AND PREPARATION METHOD AND USE THEREOF | Shandong Cynda Chemical Co., LTD. (CN) | 2016-08-31 | — | — | EP | disclosed |
| EP-3061755-A1 | A TRIKETONE COMPOUND AND PREPARATION METHOD AND USE THEREOF | Shandong Cynda Chemical Co., LTD. (CN) | 2016-08-31 | — | — | EP | disclosed |
| CN-105384687-A | Quinolinone compound and application thereof in drugs | GUANGDONG HEC PHARMACEUTICAL | 2016-03-09 | — | — | CN | disclosed |
| CN-104557739-A | Triketone compound and preparation method and application thereof | UNIV HUAZHONG NORMAL | 2015-04-29 | — | — | CN | disclosed |
| WO-2008152142-A1 | 2 -AMINOQUINAZOLINE DERIVATIVES AND THEIR THERAPEUTIC USES | SOFTCURE PHARMACEUTICALS AB (SE) | 2008-12-18 | — | — | WO | disclosed |
| WO-2008152142-A1 | 2 -AMINOQUINAZOLINE DERIVATIVES AND THEIR THERAPEUTIC USES | SOFTCURE PHARMACEUTICALS AB (SE) | 2008-12-18 | — | — | WO | disclosed |
| EP-0879815-B1 | Process for the preparation of the 5-nitro-isophthalic-di- C1-C4-alkyl esters | BAYER AG (DE) | 2000-11-02 | — | — | EP | disclosed |
| US-6002041-A | Process for preparing di-C1 - C4 -alkyl 5-nitro-isophthalates | BAYER AKTIENGESELLSCHAFT (DE) | 1999-12-14 | — | — | US | disclosed |
| EP-0879815-A1 | Process for the preparation of the 5-nitro-isophthalic-di- C1-C4-alkyl esters | BAYER AG (DE) | 1998-11-25 | — | — | EP | disclosed |
| US-4104280-A | Dibenzo [b.f]thiepin and dibenzo[b.f]oxepin derivatives | SYNTEX (U.S.A.) INC. (US) | 1978-08-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11065343-B2 | Compound bearing beta-galactoside-introduced self-immolative linker | DDOST, B3GAT3, GALNT10 | VCAM1 669/4885SIRT6 4038/4885TDP1 1893/4885 |
| US-20190328902-A1 | Compound Bearing Beta-Galactoside-Introduced Self-Immolative Linker | DDOST, B3GAT3, GALNT10 | VCAM1 669/4885SIRT6 4038/4885TDP1 1893/4885 |
| US-10065928-B2 | Quinolinone compound and use thereof | HIF1AN, HIF1A, EGLN2 | VCAM1 481/4885SIRT6 936/4885TDP1 4561/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.