Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | EDNRA | P25101 | 11/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | NSD2 | O96028 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | F2 | P00734 | 2/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4753256 | 0.75 | GAA (0.49) | HTTNSD2TSHRHSD17B10GAA | |
| SCHEMBL29437927 | 0.75 | KMT2A (0.88) | KMT2AATMCA2EDNRACYP1A2 | |
| SCHEMBL25531 | 0.75 | KMT2A (0.88) | KMT2AATMCA2EDNRACYP1A2 | |
| SCHEMBL26106116 | 0.72 | KMT2A (0.74) | KMT2AATMCA2EDNRACYP1A2 | |
| SCHEMBL32677285 | 0.72 | KMT2A (0.74) | KMT2AATMCA2EDNRACYP1A2 | |
| SCHEMBL9019311 | 0.72 | CA2 (0.71) | KMT2AATMCA2EDNRACYP1A2 | |
| SCHEMBL1131010 | 0.72 | CA2 (0.71) | KMT2AATMCA2EDNRACYP1A2 | |
| SCHEMBL6582500 | 0.71 | GAA (0.54) | KMT2ATDP1L3MBTL1KDM4EGAA | |
| SCHEMBL109002 | 0.71 | CA2 (0.69) | KMT2AATMCA2EDNRACYP1A2 | |
| SCHEMBL133520 | 0.71 | CA2 (0.69) | KMT2AATMCA2EDNRACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008144937-A1 | AUTOMATED SOLID PHASE ANALYTICAL DERIVATIZATION | MCMASTER UNIVERSITY (CA) | 2008-12-04 | — | — | WO | disclosed |