Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | NSD2 | O96028 | 7/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | EP300 | Q09472 | 1/20 | 0.33 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.33 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4753253 | 0.75 | KMT2A (0.57) | GAATSHRHTTHSD17B10NSD2 | |
| SCHEMBL25532 | 0.72 | POLB (0.58) | GAAPOLBTTRTSHRLMNA | |
| SCHEMBL29391601 | 0.71 | GAA (0.54) | GAAPKMPOLBMAPT | |
| SCHEMBL6582500 | 0.71 | GAA (0.54) | GAAPKMPOLBMAPTALDH1A1 | |
| SCHEMBL24254286 | 0.71 | GAA (0.54) | GAAPKMPOLBMAPT | |
| SCHEMBL4254051 | 0.70 | POLB (0.54) | GAAPKMPOLBTSHRLMNA | |
| SCHEMBL108422 | 0.69 | LDHA (0.64) | TTRTSHRHSD17B10NSD2ALDH1A1 | |
| SCHEMBL1525888 | 0.68 | TTR (0.78) | TTRTSHRMAPTHSD17B10NSD2 | |
| SCHEMBL31603821 | 0.68 | TTR (0.50) | GAATTRTSHRMAPTHSD17B10 | |
| SCHEMBL10730555 | 0.68 | TTR (0.50) | GAATTRTSHRHSD17B10NSD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008144937-A1 | AUTOMATED SOLID PHASE ANALYTICAL DERIVATIZATION | MCMASTER UNIVERSITY (CA) | 2008-12-04 | — | — | WO | disclosed |