Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | REN | P00797 | 2/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA4 | P22748 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4290999 | 1.00 | KMO (0.50) | KMOPOLBHSD17B10RECQLL3MBTL1 | |
| SCHEMBL4294395 | 0.94 | KMO (0.48) | KMOPOLBHSD17B10RECQLL3MBTL1 | |
| SCHEMBL4295031 | 0.89 | KMO (0.46) | KMOPOLBHSD17B10RECQLL3MBTL1 | |
| SCHEMBL13705141 | 0.86 | POLB (0.45) | KMOPOLBHSD17B10RECQLL3MBTL1 | |
| SCHEMBL13705177 | 0.80 | POLB (0.46) | KMOPOLBHSD17B10TSHRNPSR1 | |
| SCHEMBL4287498 | 0.80 | EGLN3 (0.50) | POLBHSD17B10TSHRNPC1RAB9A | |
| SCHEMBL4289440 | 0.79 | CYP11B2 (0.37) | RENKDM4EMEN1ALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL4293143 | 0.79 | LMNA (0.43) | HSD17B10TSHRSMN1; SMN2KMT2A | |
| SCHEMBL4285897 | 0.79 | KMO (0.51) | KMOPOLBHSD17B10RECQLL3MBTL1 | |
| Hydrochloric Acid SCHEMBL4292429 | 0.79 | LMNA (0.43) | HSD17B10TSHRSMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008139941-A1 | SUBSTITUTED IMIDAZOLE COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-11-20 | — | — | WO | disclosed |