Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | GBA1 | P04062 | 7/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4754102 | 0.89 | KMT2A (0.72) | MEN1KMT2AABCB1MAPTTDP1 | |
| SCHEMBL4756735 | 0.88 | KMT2A (0.58) | MEN1KMT2AABCB1MAPTTDP1 | |
| SCHEMBL4753586 | 0.84 | KMT2A (0.56) | MEN1KMT2AABCB1MAPTTDP1 | |
| SCHEMBL4090318 | 0.83 | ABCB1 (0.76) | MEN1KMT2AABCB1MAPTTDP1 | |
| SCHEMBL4753636 | 0.82 | KMT2A (0.55) | MEN1KMT2AABCB1MAPTTDP1 | |
| SCHEMBL4756892 | 0.82 | MAPT (0.61) | MEN1KMT2AABCB1MAPTTDP1 | |
| SCHEMBL4095794 | 0.80 | ABCB1 (0.55) | MEN1KMT2AABCB1MAPTTDP1 | |
| SCHEMBL4754220 | 0.78 | MEN1 (0.54) | MEN1KMT2AABCB1MAPTTDP1 | |
| SCHEMBL4753657 | 0.78 | MEN1 (0.52) | MEN1KMT2AABCB1MAPTTDP1 | |
| SCHEMBL4755807 | 0.78 | GBA1 (0.63) | MEN1KMT2AMAPTCYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008157500-A1 | AMINOQUINAZOLINE CANNABINOID RECEPTOR MODULATORS FOR TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2008-12-24 | — | — | WO | disclosed |