Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.72 |
| ▸ | MEN1 | O00255 | 4/20 | 0.72 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 5/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.51 |
| ▸ | GBA1 | P04062 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4754092 | 0.89 | MEN1 (0.58) | KMT2AMEN1ABCB1MAPTCYP1A2 | |
| SCHEMBL4756735 | 0.89 | KMT2A (0.58) | KMT2AMEN1ABCB1MAPTCYP1A2 | |
| SCHEMBL4753636 | 0.88 | KMT2A (0.55) | KMT2AMEN1ABCB1MAPTCYP1A2 | |
| SCHEMBL4753586 | 0.87 | KMT2A (0.56) | KMT2AMEN1ABCB1MAPTCYP1A2 | |
| SCHEMBL4755874 | 0.86 | HIF1A (0.67) | KMT2AMEN1ABCB1MAPTCYP1A2 | |
| SCHEMBL4092299 | 0.85 | KMT2A (0.98) | KMT2AMEN1ABCB1MAPTCYP1A2 | |
| SCHEMBL4755807 | 0.84 | GBA1 (0.63) | KMT2AMEN1MAPTCYP3A4CYP2D6 | |
| SCHEMBL4754220 | 0.84 | MEN1 (0.54) | KMT2AMEN1ABCB1MAPTCYP1A2 | |
| SCHEMBL4753657 | 0.84 | MEN1 (0.52) | KMT2AMEN1ABCB1MAPTCYP1A2 | |
| SCHEMBL4085928 | 0.83 | KMT2A (0.81) | KMT2AMEN1ABCB1MAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008157500-A1 | AMINOQUINAZOLINE CANNABINOID RECEPTOR MODULATORS FOR TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2008-12-24 | — | — | WO | disclosed |