Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | GBA1 | P04062 | 6/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4754102 | 0.89 | KMT2A (0.72) | KMT2AMEN1ABCB1MAPTABCG2 | |
| SCHEMBL4754092 | 0.88 | MEN1 (0.58) | KMT2AMEN1ABCB1MAPTABCG2 | |
| SCHEMBL4755807 | 0.85 | GBA1 (0.63) | KMT2AMEN1MAPTABCG2CYP3A4 | |
| SCHEMBL4084997 | 0.84 | ABCB1 (0.78) | KMT2AMEN1ABCB1MAPTABCG2 | |
| SCHEMBL4085547 | 0.83 | ABCB1 (0.76) | KMT2AMEN1ABCB1MAPTABCG2 | |
| SCHEMBL4756892 | 0.82 | MAPT (0.61) | KMT2AMEN1ABCB1MAPTABCG2 | |
| SCHEMBL4755906 | 0.81 | HIF1A (0.56) | KMT2AMEN1ABCB1MAPTABCG2 | |
| SCHEMBL4755874 | 0.81 | HIF1A (0.67) | KMT2AMEN1ABCB1MAPTTDP1 | |
| SCHEMBL1083864 | 0.80 | ABCB1 (0.64) | KMT2AMEN1ABCB1MAPTABCG2 | |
| SCHEMBL4091214 | 0.80 | GBA1 (0.60) | KMT2AMEN1ABCB1MAPTABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008157500-A1 | AMINOQUINAZOLINE CANNABINOID RECEPTOR MODULATORS FOR TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2008-12-24 | — | — | WO | disclosed |