Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 3/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.42 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.42 |
| ▸ | TLR5 | O60602 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4101670 | 0.90 | PDE4A (0.46) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL4102537 | 0.80 | MAPT (0.45) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL4109038 | 0.78 | MAPT (0.45) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL4752600 | 0.78 | KIF11 (0.42) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL13742519 | 0.74 | MAPT (0.41) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL5604490 | 0.72 | KIF11 (0.54) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL5489358 | 0.72 | PDE4A (0.48) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL5759177 | 0.72 | KIF11 (0.54) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL5232886 | 0.71 | KIF11 (0.51) | PDE4APDE4BPDE4CPDE4DHPGD | |
| SCHEMBL14367275 | 0.70 | PDE4A (0.69) | PDE4APDE4BPDE4CPDE4DALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008147852-A1 | KINESIN INHIBITORS | TAIGEN BIOTECHNOLOGY CO., LTD. (TW) | 2008-12-04 | — | — | WO | disclosed |