Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PROKR1 | Q8TCW9 | 16/20 | 0.48 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.47 |
| ▸ | PDE2A | O00408 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19058877 | 0.92 | PROKR1 (0.48) | PROKR1OPRL1PDE2A | |
| SCHEMBL19059098 | 0.85 | RBP4 (0.45) | PROKR1OPRL1 | |
| SCHEMBL26402882 | 0.79 | PROKR1 (0.45) | PROKR1OPRL1 | |
| SCHEMBL5226259 | 0.78 | OPRL1 (0.43) | PROKR1OPRL1 | |
| SCHEMBL3701009 | 0.78 | TACR1 (0.44) | OPRL1 | |
| SCHEMBL4153046 | 0.78 | TACR1 (0.46) | OPRL1 | |
| SCHEMBL4158017 | 0.78 | TACR1 (0.46) | OPRL1 | |
| SCHEMBL4099888 | 0.77 | RAB9A (0.57) | PROKR1 | |
| SCHEMBL21955653 | 0.76 | GSK3B (0.48) | OPRL1 | |
| SCHEMBL19442738 | 0.76 | OPRL1 (0.41) | PROKR1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008133344-A2 | PIPERIDINE DERIVATIVE AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-11-06 | — | — | WO | disclosed |