Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7889798 | 0.87 | KDM4E (0.48) | KDM4EALDH1A1HPGDHTTRECQL | |
| SCHEMBL2616850 | 0.82 | ALDH1A1 (0.53) | KDM4EALDH1A1HPGDHTTRECQL | |
| SCHEMBL7878648 | 0.80 | KDM4E (0.43) | KDM4EALDH1A1HPGDHTTRECQL | |
| SCHEMBL1899259 | 0.80 | KDM4E (0.62) | KDM4EALDH1A1HPGDHTTCYP2C9 | |
| SCHEMBL6469855 | 0.78 | KDM4E (0.49) | KDM4EALDH1A1HPGDHTTRECQL | |
| SCHEMBL6530759 | 0.77 | ALDH1A1 (0.51) | KDM4EALDH1A1HPGDCYP2C9CYP2C19 | |
| SCHEMBL3027865 | 0.76 | ALDH1A1 (0.50) | KDM4EALDH1A1HPGDHTTRECQL | |
| SCHEMBL4004075 | 0.76 | ALDH1A1 (0.50) | KDM4EALDH1A1HPGDHTTRECQL | |
| SCHEMBL3373723 | 0.76 | ALDH1A1 (0.50) | KDM4EALDH1A1HPGDHTTRECQL | |
| SCHEMBL2132706 | 0.76 | ALDH1A1 (0.50) | KDM4EALDH1A1HPGDHTTRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008157273-A1 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-12-24 | — | — | WO | disclosed |