Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7885587 | 0.87 | ALDH1A1 (0.45) | KDM4EALDH1A1HPGDHTTRECQL | |
| SCHEMBL4754864 | 0.87 | KDM4E (0.55) | KDM4EALDH1A1HPGDHTTRECQL | |
| SCHEMBL6469855 | 0.85 | KDM4E (0.49) | KDM4EALDH1A1HPGDHTTRECQL | |
| SCHEMBL9292094 | 0.84 | ALDH1A1 (0.43) | KDM4EALDH1A1HPGDHTTRECQL | |
| SCHEMBL7885220 | 0.81 | ALDH1A1 (0.51) | KDM4EALDH1A1HPGDHTTRECQL | |
| SCHEMBL7878648 | 0.80 | KDM4E (0.43) | KDM4EALDH1A1HPGDHTTRECQL | |
| SCHEMBL9293148 | 0.80 | GPR84 (0.48) | ALDH1A1HTTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL3205024 | 0.78 | ALDH1A1 (0.49) | KDM4EALDH1A1HPGDHTTRECQL | |
| SCHEMBL7309272 | 0.78 | ALDH1A1 (0.49) | KDM4EALDH1A1HPGDHTTRECQL | |
| SCHEMBL7885491 | 0.78 | ALDH1A1 (0.49) | KDM4EALDH1A1HPGDHTTRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0573218-B1 | 4-Carboxyimidazoles as angiotensin II antagonists and their thrapeutic use | SANKYO CO (JP) | 2001-03-07 | — | — | EP | disclosed |
| US-5646171-A | HYPOTENSIVE AGENTS | SANKYO COMPANY, LIMITED (JP) | 1997-07-08 | — | — | US | disclosed |
| US-5616599-A | HYPOTENSIVE AGENTS FOR CARDIOVASCULAR DISORDER | SANKYO COMPANY, LIMITED (JP) | 1997-04-01 | — | — | US | disclosed |
| EP-0313724-B1 | Bis (acyloxymethyl) imidazole Derivative | UNIV NEW YORK STATE RES FOUND (US) | 1995-08-09 | — | — | EP | disclosed |
| US-5329012-A | Bactericides, fungicides or antitumor agents | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1994-07-12 | — | — | US | disclosed |
| EP-0573218-A2 | 4-Carboxyimidazoles as angiotensin II antagonists and their thrapeutic use | SANKYO COMPANY LIMITED (JP) | 1993-12-08 | — | — | EP | disclosed |
| EP-0313724-A2 | Bis (acyloxymethyl) imidazole Derivative | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1989-05-03 | — | — | EP | disclosed |