Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4754950 | 1.00 | DHFR (0.41) | DHFRSQSTM1 | |
| SCHEMBL4753592 | 0.81 | DHFR (0.47) | DHFRSQSTM1 | |
| SCHEMBL4753839 | 0.81 | DHFR (0.50) | DHFRSQSTM1 | |
| SCHEMBL4756475 | 0.79 | DHFR (0.49) | DHFRSQSTM1 | |
| SCHEMBL4754944 | 0.73 | DHFR (0.44) | DHFR | |
| SCHEMBL4754987 | 0.73 | SQSTM1 (0.45) | DHFRSQSTM1 | |
| SCHEMBL4756452 | 0.70 | SQSTM1 (0.48) | DHFRSQSTM1 | |
| SCHEMBL4756382 | 0.70 | DHFR (0.52) | DHFR | |
| SCHEMBL4755174 | 0.68 | SQSTM1 (0.48) | DHFRSQSTM1 | |
| SCHEMBL4753607 | 0.66 | DHFR (0.45) | DHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008152142-A1 | 2 -AMINOQUINAZOLINE DERIVATIVES AND THEIR THERAPEUTIC USES | SOFTCURE PHARMACEUTICALS AB (SE) | 2008-12-18 | — | — | WO | disclosed |