Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPN1 | P15169 | 1/20 | 0.46 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | PREP | P48147 | 1/20 | 0.36 |
| ▸ | FAP | Q12884 | 1/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.33 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.33 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27195379 | 0.98 | CPN1 (0.45) | CPN1CPB2ALDH1A1NPC1DPP4 | |
| SCHEMBL16405710 | 0.82 | ALDH1A1 (0.37) | ALDH1A1NPC1SMN1; SMN2L3MBTL1TDP1 | |
| SCHEMBL2702633 | 0.82 | CPN1 (0.47) | CPN1CPB2ALDH1A1NPC1DPP4 | |
| SCHEMBL15808560 | 0.81 | CPN1 (0.46) | CPN1CPB2ALDH1A1NPC1DPP4 | |
| SCHEMBL24521448 | 0.78 | MEN1 (0.40) | CPN1CPB2ALDH1A1DPP4PREP | |
| SCHEMBL3904549 | 0.77 | CPN1 (0.53) | CPN1CPB2ALDH1A1NPC1DPP4 | |
| SCHEMBL18525068 | 0.77 | EPHX2 (0.42) | ALDH1A1NPC1POLB | |
| SCHEMBL20117157 | 0.76 | L3MBTL1 (0.54) | CPN1CPB2ALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL9492517 | 0.76 | GAA (0.55) | CPN1CPB2ALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL1163329 | 0.75 | LMNA (0.32) | ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633348-B1 | 4- BROMO - 5 - (2- CHLORO - BENZOYLAMINO) - 1H - PYRAZOLE - 3 - CARBOXYLIC ACID AMIDE DERIVATIVES AND RELATED COMPOUNDS AS BRADYKININ B sb 1 /sb RECEPTOR ANTAGONISTS FOR THE TREATMENT OF INFLAMMATORY DISEASES | ELAN PHARM INC (US) | 2008-10-08 | — | — | EP | claimed |