Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | ACACB | O00763 | 6/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 3/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4755482 | 0.90 | PPARG (0.47) | MEN1KMT2ATDP1ACACBPPARA | |
| SCHEMBL947174 | 0.85 | FFAR1 (0.55) | TDP1SMN1; SMN2PPARAPPARGPPARD | |
| SCHEMBL28874725 | 0.85 | LDHA (0.51) | MEN1KMT2ATDP1ACACBSMN1; SMN2 | |
| SCHEMBL28305791 | 0.83 | CYP2A6 (0.44) | MEN1KMT2ATDP1ACACBSMN1; SMN2 | |
| SCHEMBL27548183 | 0.83 | SMN1; SMN2 (0.44) | MEN1KMT2ATDP1ACACBSMN1; SMN2 | |
| SCHEMBL5992779 | 0.82 | PPARA (0.62) | MEN1KMT2AACACBPPARAPPARG | |
| SCHEMBL7041549 | 0.82 | MEN1 (0.48) | MEN1KMT2ATDP1ACACBTP53 | |
| SCHEMBL6818027 | 0.81 | ESR1 (0.46) | MEN1KMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL4789672 | 0.81 | LTA4H (0.43) | MEN1KMT2ATDP1ACACBSMN1; SMN2 | |
| SCHEMBL4789667 | 0.81 | LTA4H (0.43) | MEN1KMT2ATDP1ACACBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008010238-A2 | ANTIDIABETIC AZABICYCLO [3. 1. 0] HEXAN COMPOUNDS | LUPIN LIMITED (IN) | 2008-01-24 | — | — | WO | disclosed |
| WO-2008010238-A2 | ANTIDIABETIC AZABICYCLO [3. 1. 0] HEXAN COMPOUNDS | LUPIN LIMITED (IN) | 2008-01-24 | — | — | WO | disclosed |