Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.35 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4757759 | 0.80 | CCR1 (0.43) | CCR1CHRM3CHRM2CHRM1KCNA3 | |
| SCHEMBL4756747 | 0.79 | CHRM3 (0.47) | CHRM3CYP2D6CHRM2CHRM1OPRM1 | |
| SCHEMBL4755434 | 0.78 | CHRM3 (0.41) | CCR1KEAP1NFE2L2CHRM3CHRM2 | |
| SCHEMBL13123944 | 0.75 | CCR1 (0.48) | CCR1KEAP1NFE2L2CHRM3CYP2D6 | |
| SCHEMBL9665195 | 0.75 | CCR1 (0.48) | CCR1KEAP1NFE2L2CHRM3CYP2D6 | |
| SCHEMBL4756790 | 0.74 | CHRM3 (0.39) | CCR1CHRM3CYP2D6CHRM2CHRM1 | |
| SCHEMBL9667151 | 0.74 | CCR1 (0.47) | CCR1KEAP1NFE2L2CHRM3CYP2D6 | |
| SCHEMBL5754340 | 0.72 | KEAP1 (0.47) | CCR1KEAP1NFE2L2CHRM3CYP2D6 | |
| SCHEMBL5751962 | 0.72 | CCR1 (0.46) | CCR1KEAP1NFE2L2CHRM3CYP2D6 | |
| SCHEMBL8073914 | 0.70 | CCR1 (0.45) | CCR1KEAP1NFE2L2CHRM3CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008117229-A1 | MUSCARINIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2008-10-02 | — | — | WO | disclosed |