SCHEMBL4755637

SCHEMBL4755637

O=CC=CCC(c1ccccc1)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.41
TRPA1 O75762 1/20 0.41
ALDH1A1 P00352 1/20 0.41
ALOX5 P09917 1/20 0.41
MAPK1 P28482 1/20 0.41
HTR2A P28223 6/20 0.39
TAAR1 Q96RJ0 1/20 0.39
CYP2D6 P10635 1/20 0.38
CYP2C19 P33261 1/20 0.37
HRH1 P35367 5/20 0.37
GRIN1 Q05586 2/20 0.35
GRIN2A Q12879 2/20 0.35
KDM4E B2RXH2 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
POLB P06746 1/20 0.34
CCNB2 O95067 1/20 0.33
CDK1 P06493 1/20 0.33
CDK4 P11802 1/20 0.33
CCNB1 P14635 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10372161 0.82 KDM4E (0.48) LMNAMAPK1CYP2D6CYP2C19KDM4E
SCHEMBL10454477 0.82 TAAR1 (0.45) LMNATRPA1ALDH1A1ALOX5MAPK1
SCHEMBL6257167 0.77 CHRNB2 (0.42) LMNATRPA1ALDH1A1ALOX5MAPK1
SCHEMBL68782 0.77 HTR2A (0.46) HTR2ATAAR1CYP2D6CYP2C19HRH1
SCHEMBL6718630 0.73 HTR2A (0.42) LMNAHTR2ATAAR1CYP2C19HRH1
SCHEMBL6718628 0.73 HTR2A (0.42) LMNAHTR2ATAAR1CYP2C19HRH1
SCHEMBL7238650 0.72 HCAR2 (0.44) LMNAALDH1A1MAPK1CYP2D6CYP2C19
SCHEMBL7239259 0.72 HCAR2 (0.44) LMNAALDH1A1MAPK1CYP2D6CYP2C19
SCHEMBL3144362 0.72 HCAR2 (0.44) LMNAALDH1A1MAPK1CYP2D6CYP2C19
SCHEMBL6905011 0.72 ALDH1A1 (0.46) LMNATRPA1ALDH1A1ALOX5MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009002276-A1 PROCESS FOR ALDOL CONDENSATION FOR PREPARATION OF α,β-UNSATURATED ALDEHYDE OR KETONE AND APPLICATION THEREOF IN SYNTHESIS OF SUBSTITUTED PYRROLE OR ARYLATION OF α,β-UNSATURATED ENAL AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2008-12-31 WO disclosed