Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 7/20 | 0.37 |
| ▸ | PTPN2 | P17706 | 4/20 | 0.37 |
| ▸ | PTPN6 | P29350 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HMGB1 | P09429 | 2/20 | 0.36 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.34 |
| ▸ | ERN1 | O75460 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4756950 | 0.81 | ALDH1A1 (0.41) | ALDH1A1HPGDHSD17B10PTPN1PTPN2 | |
| SCHEMBL4755008 | 0.81 | ALDH1A1 (0.43) | ALDH1A1HPGDHSD17B10PTPN1PTPN2 | |
| SCHEMBL1982021 | 0.74 | KDM4E (0.55) | ALDH1A1HPGDHSD17B10PTPN1PTPN2 | |
| SCHEMBL2523153 | 0.74 | KDM4E (0.55) | ALDH1A1HPGDHSD17B10PTPN1PTPN2 | |
| SCHEMBL1981806 | 0.73 | PKM (0.51) | ALDH1A1HPGDPTPN1PTPN2PTPN6 | |
| SCHEMBL29954196 | 0.73 | PKM (0.51) | ALDH1A1HPGDPTPN1PTPN2PTPN6 | |
| SCHEMBL31247877 | 0.72 | ALDH1A1 (0.53) | ALDH1A1HPGDRAB9ANPSR1KDM4E | |
| SCHEMBL9687007 | 0.72 | PKM (0.50) | ALDH1A1HPGDPTPN1PTPN2PTPN6 | |
| SCHEMBL9686354 | 0.72 | PKM (0.50) | ALDH1A1HPGDPTPN1PTPN2PTPN6 | |
| SCHEMBL4755647 | 0.71 | HCAR2 (0.38) | HCAR2ALDH1A1HMGB1CXCL12ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879661-A1 | AGENT FOR DYEING KERATIN-BASED FIBRES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2008-01-23 | — | — | EP | claimed |
| WO-2006119821-A1 | AGENT FOR DYEING KERATIN-BASED FIBRES | HENKEL KOMMANDITGESELLCHAFT AUF AKTIEN (DE) | 2006-11-16 | — | — | WO | claimed |